Your Account
Community
Topics (Upcoming)
More |
Welcome to CardiologyLinks.NETCardiologyLinks.NET is a user powered cardiology news portal. On this social content voting site, all news is submitted by its users. Any member can submit cardiology related content to CardiologyLinks.NET, and this will enable the content to be viewed by all. The content will be promoted or buried depending on how much it is liked by the community. The more votes the submission gets, the more popular it is. With enough votes, the piece of news will be showcased on the Front page of CardiologyLinks.NET. Submit any Cardiology News or Links now! If you are looking for a specific topic news, then please use the search box at the top right corner of this page.
ABCG1 Deficiency in Mice Promotes Endothelial Activation and Monocyte-Endothelial Interactions [Cell
1 / 0
 
http://atvb.ahajournals.org/cgi/content/short/30/4/809?rss=1
Objective— Activated endothelium and increased monocyte–endothelial interactions in the vessel wall are key early events in atherogenesis. ATP binding cassette (ABC) transporters play important roles in regulating sterol homeostasis in many cell types. Endothelial cells (EC) have a high capacity to efflux sterols and express the ABC transporter, ABCG1...
Join discussion...
Nutrient Modification of the Innate Immune Response: A Novel Mechanism by Which Saturated Fatty Acid
1 / 0
http://atvb.ahajournals.org/cgi/content/short/30/4/802?rss=1
Objective— Monocyte/macrophage inflammation is an important contributor to diabetes and cardiovascular disease. Studies have suggested saturated fatty acids (SFA) induce monocyte inflammation in a Toll-like receptor-4–dependent manner, but recent data suggest SFA do not directly interact with Toll-like receptor-4. The present study tests...
Join discussion...
The Ability to Promote Efflux Via ABCA1 Determines the Capacity of Serum Specimens With Similar High
1 / 0
http://atvb.ahajournals.org/cgi/content/short/30/4/796?rss=1
Objective— We measured efflux from macrophages to apolipoprotein B-depleted serum from 263 specimens and found instances in which serum having similar high-density lipoprotein cholesterol (HDL-C) differed in their efflux capacity. Thus, we wanted to elucidate why efflux capacity could be independent of total HDL-C or apolipoprotein A-I (apoA-I)...
Join discussion...
Macrophage LRP-1 Controls Plaque Cellularity by Regulating Efferocytosis and Akt Activation [Integra
1 / 0
http://atvb.ahajournals.org/cgi/content/short/30/4/787?rss=1
Objective— The balance between apoptosis susceptibility and efferocytosis of macrophages is central to plaque remodeling and inflammation. LRP-1 and its ligand, apolipoprotein E, have been implicated in efferocytosis and apoptosis in some cell types. We investigated the involvement of the macrophage LRP-1/apolipoprotein E axis in controlling plaque apoptosis and efferocytosis...
Join discussion...
Tissue-Specific Liver X Receptor Activation Promotes Macrophage Reverse Cholesterol Transport In Viv
1 / 0
http://atvb.ahajournals.org/cgi/content/short/30/4/781?rss=1
Objective— We previously reported that a systemic liver X receptor (LXR) agonist promoted macrophage reverse-cholesterol transport (mRCT) in vivo. Because LXR are expressed in multiple tissues involved in RCT (macrophages, liver, intestine), we analyzed the effect of tissue-specific LXR agonism on mRCT.
Methods and Results— In initial studies...
Join discussion...
Enhanced External Counterpulsation Attenuates Atherosclerosis Progression Through Modulation of Proi
1 / 0
http://atvb.ahajournals.org/cgi/content/short/30/4/773?rss=1
Objective— Shear stress may be the most crucial local factor affecting atherogenesis. The present study investigated the effect of exposure to increased shear stress promoted by enhanced external counterpulsation (EECP) on the progression of atherosclerosis and the underlying inflammation-related molecular mechanisms in a porcine model of hypercholesterolemia...
Join discussion...
Nonenzymatic Glycation Impairs the Antiinflammatory Properties of Apolipoprotein A-I [Integrative Ph
1 / 0
http://atvb.ahajournals.org/cgi/content/short/30/4/766?rss=1
Objective— The goal of this study was to investigate the effects of nonenzymatic glycation on the antiinflammatory properties of apolipoprotein (apo) A-I.
Methods and Results— Rabbits were infused with saline, lipid-free apoA-I from normal subjects (apoA-IN), lipid-free apoA-I nonenzymatically glycated by incubation with methylglyoxal (apoA...
Join discussion...
Reduced NO-cGMP Signaling Contributes to Vascular Inflammation and Insulin Resistance Induced by Hig
1 / 0
http://atvb.ahajournals.org/cgi/content/short/30/4/758?rss=1
Objective— Diet-induced obesity (DIO) in mice causes vascular inflammation and insulin resistance that are accompanied by decreased endothelial-derived NO production. We sought to determine whether reduced NO-cGMP signaling contributes to the deleterious effects of DIO on the vasculature and, if so, whether these effects can be blocked by increased vascular NO-cGMP signaling...
Join discussion...
Specific Dietary Polyphenols Attenuate Atherosclerosis in Apolipoprotein E-Knockout Mice by Alleviat
1 / 0
http://atvb.ahajournals.org/cgi/content/short/30/4/749?rss=1
Objective— Animal and clinical studies have suggested that polyphenols in fruits, red wine, and tea may delay the development of atherosclerosis through their antioxidant and anti-inflammatory properties. We investigated whether individual dietary polyphenols representing different polyphenolic classes, namely quercetin (flavonol), (–)-epicatechin...
Join discussion...
Naringenin Decreases Progression of Atherosclerosis by Improving Dyslipidemia in High-Fat-Fed Low-De
1 / 0
http://atvb.ahajournals.org/cgi/content/short/30/4/742?rss=1
Objective— Naringenin is a citrus flavonoid that potently inhibits the assembly and secretion of apolipoprotein B100–containing lipoproteins in cultured hepatocytes and improves the dyslipidemia and insulin resistance in a mouse model of the metabolic syndrome. In the present study, we used low-density lipoprotein receptor–null mice...
Join discussion...
|
© 2008 CardiologyLinks.NET
