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Left Ventricular and Myocardial Function in Mice Expressing Constitutively Pseudophosphorylated Card
http://circres.ahajournals.org/cgi/content/short/105/12/1232...
Submitted by
cardiologylinks
7 months, 3 weeks, 6 days, 12 hours agoRationale: Protein kinase (PK)C-induced phosphorylation of cardiac troponin (cTn)I has been shown to regulate cardiac contraction.
Objective: Characterize functional effects of increased PKC-induced cTnI phosphorylation and identify underlying mechanisms using a transgenic mouse model (cTnIPKC-P) expressing mutant cTnI (S43E, S45E, T144E).
Methods and...
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#1 - By alka sori, 7 months, 1 week, 2 days, 2 hours ago.
cardiology is my interest area
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