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View news or links Left Ventricular and Myocardial Function in Mice Expressing Constitutively Pseudophosphorylated Card 1 / 0 http://circres.ahajournals.org/cgi/content/short/105/12/1232... Submitted by cardiologylinks 9 months, 1 week, 1 day, 4 hours ago Rationale: Protein kinase (PK)C-induced phosphorylation of cardiac troponin (cTn)I has been shown to regulate cardiac contraction. Objective: Characterize functional effects of increased PKC-induced cTnI phosphorylation and identify underlying mechanisms using a transgenic mouse model (cTnIPKC-P) expressing mutant cTnI (S43E, S45E, T144E). Methods and... Tags: cardiology comment (1) | Category: Cardiology | Add cardiologylinks as a friend Comments Votes (my friends) Votes (Everyone) « go back

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